Tests selected genetic variants in the Factor V (F5), prothrombin (F2) and MTHFR genes associated with inherited differences relevant to thrombosis or homocysteine metabolism.
Used to assess inherited thrombophilia associated with Factor V Leiden and prothrombin variants in selected people with suspected or familial thrombosis. Common MTHFR variants have limited clinical utility for assessing blood-clot risk and should not be interpreted as equivalent thrombophilia markers.